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Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integration

We present a coarse-grained simulation model that is capable of simulating the minute-timescale dynamics of protein translocation and membrane integration via the Sec translocon, while retaining sufficient chemical and structural detail to capture many of the sequence-specific interactions that driv...

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Detalles Bibliográficos
Autores principales:	Niesen, Michiel J. M., Wang, Connie Y., Van Lehn, Reid C., Miller, Thomas F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381951/ https://www.ncbi.nlm.nih.gov/pubmed/28328943 http://dx.doi.org/10.1371/journal.pcbi.1005427

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