Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Mucoadhesive particles (MAP) have been widely explored for pulmonary drug delivery because of their perceived benefits in improving particle residence in the lungs. However, retention of particles adhesively trapped in airway mucus may be limited by physiologic mucus clearance mechanisms. In contras...

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Detalles Bibliográficos
Autores principales: Schneider, Craig S., Xu, Qingguo, Boylan, Nicholas J., Chisholm, Jane, Tang, Benjamin C., Schuster, Benjamin S., Henning, Andreas, Ensign, Laura M., Lee, Ethan, Adstamongkonkul, Pichet, Simons, Brian W., Wang, Sho-Yu S., Gong, Xiaoqun, Yu, Tao, Boyle, Michael P., Suk, Jung Soo, Hanes, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381952/
https://www.ncbi.nlm.nih.gov/pubmed/28435870
http://dx.doi.org/10.1126/sciadv.1601556

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