Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

Traditional response criteria in MDS and AML are based on bone marrow morphology and may not accurately reflect clonal tumor burden in patients treated with non-cytotoxic chemotherapy. We used next-generation sequencing of serial bone marrow samples to monitor MDS and AML tumor burden during treatme...

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Detalles Bibliográficos
Autores principales: Uy, Geoffrey L., Duncavage, Eric J., Chang, Gue Su, Jacoby, Meagan A., Miller, Christopher A., Shao, Jin, Heath, Sharon, Elliott, Kevin, Reinick, Teresa, Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Ganel, Liron, Abboud, Camille N., Cashen, Amanda F., DiPersio, John F., Wilson, Richard K, Link, Daniel C., Welch, John S., Ley, Timothy J., Graubert, Timothy A., Westervelt, Peter, Walter, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382101/
https://www.ncbi.nlm.nih.gov/pubmed/27740633
http://dx.doi.org/10.1038/leu.2016.282

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