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P2X(1), P2X(4), and P2X(7) Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli

α-haemolysin (HlyA)-producing Escherichia coli commonly inflict severe urinary tract infections, including pyelonephritis, which comprises substantial risk for sepsis. In vitro, the cytolytic effect of HlyA is mainly mediated by ATP release through the HlyA pore and subsequent P2X(1)/P2X(7) receptor...

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Detalles Bibliográficos
Autores principales:	Greve, Anne-Sofie, Skals, Marianne, Fagerberg, Steen K., Tonnus, Wulf, Ellermann-Eriksen, Svend, Evans, Richard J., Linkermann, Andreas, Praetorius, Helle A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382212/ https://www.ncbi.nlm.nih.gov/pubmed/28428949 http://dx.doi.org/10.3389/fcimb.2017.00113

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