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Glutaredoxin catalysis requires two distinct glutathione interaction sites

Glutaredoxins are key players in cellular redox homoeostasis and exert a variety of essential functions ranging from glutathione-dependent catalysis to iron metabolism. The exact structure–function relationships and mechanistic differences among glutaredoxins that are active or inactive in standard...

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Detalles Bibliográficos
Autores principales: Begas, Patricia, Liedgens, Linda, Moseler, Anna, Meyer, Andreas J., Deponte, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382279/
https://www.ncbi.nlm.nih.gov/pubmed/28374771
http://dx.doi.org/10.1038/ncomms14835

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