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Glutaredoxin catalysis requires two distinct glutathione interaction sites
Glutaredoxins are key players in cellular redox homoeostasis and exert a variety of essential functions ranging from glutathione-dependent catalysis to iron metabolism. The exact structure–function relationships and mechanistic differences among glutaredoxins that are active or inactive in standard...
Autores principales: | Begas, Patricia, Liedgens, Linda, Moseler, Anna, Meyer, Andreas J., Deponte, Marcel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382279/ https://www.ncbi.nlm.nih.gov/pubmed/28374771 http://dx.doi.org/10.1038/ncomms14835 |
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