Cargando…
Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD
In previous work, we identified 145 active compounds from Bufei Jianpi formula (BJF) by system pharmacology and found that BJF showed short-term effect on chronic obstructive pulmonary disease (COPD) rats. Here, we applied the transcriptomic, proteomic, and metabolomics approaches to illustrate the...
Autores principales: | Zhao, Peng, Li, Jiansheng, Li, Ya, Tian, Yange, Yang, Liping, Li, Suyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382313/ https://www.ncbi.nlm.nih.gov/pubmed/28424787 http://dx.doi.org/10.1155/2017/7091087 |
Ejemplares similares
-
Combining systems pharmacology, transcriptomics, proteomics, and metabolomics to dissect the therapeutic mechanism of Chinese herbal Bufei Jianpi formula for application to COPD
por: Zhao, Peng, et al.
Publicado: (2016) -
Systems pharmacology-based approach for dissecting the active ingredients and potential targets of the Chinese herbal Bufei Jianpi formula for the treatment of COPD
por: Zhao, Peng, et al.
Publicado: (2015) -
Integration of transcriptomics, proteomics, metabolomics and systems pharmacology data to reveal the therapeutic mechanism underlying Chinese herbal Bufei Yishen formula for the treatment of chronic obstructive pulmonary disease
por: Zhao, Peng, et al.
Publicado: (2018) -
Bufei Jianpi granules improve skeletal muscle and mitochondrial dysfunction in rats with chronic obstructive pulmonary disease
por: Dong, Yuqiong, et al.
Publicado: (2015) -
System biology analysis of long-term effect and mechanism of Bufei Yishen on COPD revealed by system pharmacology and 3-omics profiling
por: Li, Jiansheng, et al.
Publicado: (2016)