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Microglia activation is essential for BMP7-mediated retinal reactive gliosis

BACKGROUND: Our previous studies have shown that BMP7 is able to trigger activation of retinal macroglia. However, these studies showed the responsiveness of Müller glial cells and retinal astrocytes in vitro was attenuated in comparison to those in vivo, indicating other retinal cell types may be m...

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Detalles Bibliográficos
Autores principales: Dharmarajan, Subramanian, Fisk, Debra L., Sorenson, Christine M., Sheibani, Nader, Belecky-Adams, Teri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382432/
https://www.ncbi.nlm.nih.gov/pubmed/28381236
http://dx.doi.org/10.1186/s12974-017-0855-0