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Vaccination against parasites – status quo and the way forward
Although vaccination against various pathogens is integral to health management of swine, vaccines against parasites have not yet been commercialized for the use in pigs. The incentive to develop and commercialize anti-parasitic vaccines in swine are twofold; on the one hand parasitic diseases which...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382507/ https://www.ncbi.nlm.nih.gov/pubmed/28405456 http://dx.doi.org/10.1186/s40813-016-0047-9 |
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author | Joachim, Anja |
author_facet | Joachim, Anja |
author_sort | Joachim, Anja |
collection | PubMed |
description | Although vaccination against various pathogens is integral to health management of swine, vaccines against parasites have not yet been commercialized for the use in pigs. The incentive to develop and commercialize anti-parasitic vaccines in swine are twofold; on the one hand parasitic diseases which are economically important, such as ascarosis and neonatal coccidiosis, could be controlled in a sustainable manner; on the other hand, the transmission of zoonotic parasites, such as Toxoplasma gondii or Cysticercus cellulosae, could be effectively interrupted. Although experimental research indicates that vaccination against a number of porcine parasites is feasible, development and commercialization of potential vaccines so far has been very slow, as our knowledge on the host-parasite interplay in porcine parasitic infections is still very limited. In the light of growing concerns regarding consumer health and antiparasitic drug resistance, however, it is timely to re-direct R&D efforts to the development of biological control options. |
format | Online Article Text |
id | pubmed-5382507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-53825072017-04-12 Vaccination against parasites – status quo and the way forward Joachim, Anja Porcine Health Manag Review Although vaccination against various pathogens is integral to health management of swine, vaccines against parasites have not yet been commercialized for the use in pigs. The incentive to develop and commercialize anti-parasitic vaccines in swine are twofold; on the one hand parasitic diseases which are economically important, such as ascarosis and neonatal coccidiosis, could be controlled in a sustainable manner; on the other hand, the transmission of zoonotic parasites, such as Toxoplasma gondii or Cysticercus cellulosae, could be effectively interrupted. Although experimental research indicates that vaccination against a number of porcine parasites is feasible, development and commercialization of potential vaccines so far has been very slow, as our knowledge on the host-parasite interplay in porcine parasitic infections is still very limited. In the light of growing concerns regarding consumer health and antiparasitic drug resistance, however, it is timely to re-direct R&D efforts to the development of biological control options. BioMed Central 2016-12-15 /pmc/articles/PMC5382507/ /pubmed/28405456 http://dx.doi.org/10.1186/s40813-016-0047-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Joachim, Anja Vaccination against parasites – status quo and the way forward |
title | Vaccination against parasites – status quo and the way forward |
title_full | Vaccination against parasites – status quo and the way forward |
title_fullStr | Vaccination against parasites – status quo and the way forward |
title_full_unstemmed | Vaccination against parasites – status quo and the way forward |
title_short | Vaccination against parasites – status quo and the way forward |
title_sort | vaccination against parasites – status quo and the way forward |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382507/ https://www.ncbi.nlm.nih.gov/pubmed/28405456 http://dx.doi.org/10.1186/s40813-016-0047-9 |
work_keys_str_mv | AT joachimanja vaccinationagainstparasitesstatusquoandthewayforward |