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Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease
The effects of capsaicin (CAP), a transient receptor potential vanilloid subtype 1 (TRPV1) agonist, were determined on nigrostriatal dopamine (DA) neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease (PD). The results showed that TRPV1 activation...
Autores principales: | Chung, Young C, Baek, Jeong Y, Kim, Sang R, Ko, Hyuk W, Bok, Eugene, Shin, Won-Ho, Won, So-Yoon, Jin, Byung K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382554/ https://www.ncbi.nlm.nih.gov/pubmed/28255166 http://dx.doi.org/10.1038/emm.2016.159 |
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