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Progress of antibody-based inhibitors of the HGF–cMET axis in cancer therapy
Dysregulated receptor tyrosine kinase signaling in human cancer cells leads to tumor progression, invasion and metastasis. The receptor tyrosine kinase cMET is frequently overexpressed in cancer tissue, and activation of cMET signaling is related to drug resistance and the processes of carcinogenesi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382561/ https://www.ncbi.nlm.nih.gov/pubmed/28336955 http://dx.doi.org/10.1038/emm.2017.17 |