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Suppressor of Cytokine Signaling 2 Negatively Regulates NK Cell Differentiation by Inhibiting JAK2 Activity

Suppressor of cytokine signaling (SOCS) proteins are negative regulators of cytokine responses. Although recent reports have shown regulatory roles for SOCS proteins in innate and adaptive immunity, their roles in natural killer (NK) cell development are largely unknown. Here, we show that SOCS2 is...

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Detalles Bibliográficos
Autores principales: Kim, Won Sam, Kim, Mi Jeong, Kim, Dong Oh, Byun, Jae-Eun, Huy, Hangsak, Song, Hae Young, Park, Young-Jun, Kim, Tae-Don, Yoon, Suk Ran, Choi, Eun-Ji, Jung, Haiyoung, Choi, Inpyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382670/
https://www.ncbi.nlm.nih.gov/pubmed/28383049
http://dx.doi.org/10.1038/srep46153