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DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized by senile plaques, neurofibrillary tangles, synaptic disruption, and neuronal loss. Several studies have demonstrated decreases of docosahexaenoic acid-containing phosphatidylcholines (DHA-PCs) in the AD b...

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Detalles Bibliográficos
Autores principales: Yuki, Dai, Sugiura, Yuki, Zaima, Nobuhiro, Akatsu, Hiroyasu, Takei, Shiro, Yao, Ikuko, Maesako, Masato, Kinoshita, Ayae, Yamamoto, Takayuki, Kon, Ryo, Sugiyama, Keikichi, Setou, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382699/
https://www.ncbi.nlm.nih.gov/pubmed/25410733
http://dx.doi.org/10.1038/srep07130