Successful Treatment of Human Plague with Oral Ciprofloxacin

The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, includ...

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Detalles Bibliográficos
Autores principales: Apangu, Titus, Griffith, Kevin, Abaru, Janet, Candini, Gordian, Apio, Harriet, Okoth, Felix, Okello, Robert, Kaggwa, John, Acayo, Sarah, Ezama, Geoffrey, Yockey, Brook, Sexton, Christopher, Schriefer, Martin, Mbidde, Edward Katongole, Mead, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382724/
https://www.ncbi.nlm.nih.gov/pubmed/28125398
http://dx.doi.org/10.3201/eid2303.161212
Descripción
Sumario:The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.

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