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Successful Treatment of Human Plague with Oral Ciprofloxacin

The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, includ...

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Detalles Bibliográficos
Autores principales: Apangu, Titus, Griffith, Kevin, Abaru, Janet, Candini, Gordian, Apio, Harriet, Okoth, Felix, Okello, Robert, Kaggwa, John, Acayo, Sarah, Ezama, Geoffrey, Yockey, Brook, Sexton, Christopher, Schriefer, Martin, Mbidde, Edward Katongole, Mead, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382724/
https://www.ncbi.nlm.nih.gov/pubmed/28125398
http://dx.doi.org/10.3201/eid2303.161212
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author Apangu, Titus
Griffith, Kevin
Abaru, Janet
Candini, Gordian
Apio, Harriet
Okoth, Felix
Okello, Robert
Kaggwa, John
Acayo, Sarah
Ezama, Geoffrey
Yockey, Brook
Sexton, Christopher
Schriefer, Martin
Mbidde, Edward Katongole
Mead, Paul
author_facet Apangu, Titus
Griffith, Kevin
Abaru, Janet
Candini, Gordian
Apio, Harriet
Okoth, Felix
Okello, Robert
Kaggwa, John
Acayo, Sarah
Ezama, Geoffrey
Yockey, Brook
Sexton, Christopher
Schriefer, Martin
Mbidde, Edward Katongole
Mead, Paul
author_sort Apangu, Titus
collection PubMed
description The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.
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spelling pubmed-53827242017-04-06 Successful Treatment of Human Plague with Oral Ciprofloxacin Apangu, Titus Griffith, Kevin Abaru, Janet Candini, Gordian Apio, Harriet Okoth, Felix Okello, Robert Kaggwa, John Acayo, Sarah Ezama, Geoffrey Yockey, Brook Sexton, Christopher Schriefer, Martin Mbidde, Edward Katongole Mead, Paul Emerg Infect Dis Research Letter The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague. Centers for Disease Control and Prevention 2017-03 /pmc/articles/PMC5382724/ /pubmed/28125398 http://dx.doi.org/10.3201/eid2303.161212 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Apangu, Titus
Griffith, Kevin
Abaru, Janet
Candini, Gordian
Apio, Harriet
Okoth, Felix
Okello, Robert
Kaggwa, John
Acayo, Sarah
Ezama, Geoffrey
Yockey, Brook
Sexton, Christopher
Schriefer, Martin
Mbidde, Edward Katongole
Mead, Paul
Successful Treatment of Human Plague with Oral Ciprofloxacin
title Successful Treatment of Human Plague with Oral Ciprofloxacin
title_full Successful Treatment of Human Plague with Oral Ciprofloxacin
title_fullStr Successful Treatment of Human Plague with Oral Ciprofloxacin
title_full_unstemmed Successful Treatment of Human Plague with Oral Ciprofloxacin
title_short Successful Treatment of Human Plague with Oral Ciprofloxacin
title_sort successful treatment of human plague with oral ciprofloxacin
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382724/
https://www.ncbi.nlm.nih.gov/pubmed/28125398
http://dx.doi.org/10.3201/eid2303.161212
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