Cargando…
Successful Treatment of Human Plague with Oral Ciprofloxacin
The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, includ...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382724/ https://www.ncbi.nlm.nih.gov/pubmed/28125398 http://dx.doi.org/10.3201/eid2303.161212 |
_version_ | 1782520154144374784 |
---|---|
author | Apangu, Titus Griffith, Kevin Abaru, Janet Candini, Gordian Apio, Harriet Okoth, Felix Okello, Robert Kaggwa, John Acayo, Sarah Ezama, Geoffrey Yockey, Brook Sexton, Christopher Schriefer, Martin Mbidde, Edward Katongole Mead, Paul |
author_facet | Apangu, Titus Griffith, Kevin Abaru, Janet Candini, Gordian Apio, Harriet Okoth, Felix Okello, Robert Kaggwa, John Acayo, Sarah Ezama, Geoffrey Yockey, Brook Sexton, Christopher Schriefer, Martin Mbidde, Edward Katongole Mead, Paul |
author_sort | Apangu, Titus |
collection | PubMed |
description | The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague. |
format | Online Article Text |
id | pubmed-5382724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-53827242017-04-06 Successful Treatment of Human Plague with Oral Ciprofloxacin Apangu, Titus Griffith, Kevin Abaru, Janet Candini, Gordian Apio, Harriet Okoth, Felix Okello, Robert Kaggwa, John Acayo, Sarah Ezama, Geoffrey Yockey, Brook Sexton, Christopher Schriefer, Martin Mbidde, Edward Katongole Mead, Paul Emerg Infect Dis Research Letter The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague. Centers for Disease Control and Prevention 2017-03 /pmc/articles/PMC5382724/ /pubmed/28125398 http://dx.doi.org/10.3201/eid2303.161212 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Letter Apangu, Titus Griffith, Kevin Abaru, Janet Candini, Gordian Apio, Harriet Okoth, Felix Okello, Robert Kaggwa, John Acayo, Sarah Ezama, Geoffrey Yockey, Brook Sexton, Christopher Schriefer, Martin Mbidde, Edward Katongole Mead, Paul Successful Treatment of Human Plague with Oral Ciprofloxacin |
title | Successful Treatment of Human Plague with Oral Ciprofloxacin |
title_full | Successful Treatment of Human Plague with Oral Ciprofloxacin |
title_fullStr | Successful Treatment of Human Plague with Oral Ciprofloxacin |
title_full_unstemmed | Successful Treatment of Human Plague with Oral Ciprofloxacin |
title_short | Successful Treatment of Human Plague with Oral Ciprofloxacin |
title_sort | successful treatment of human plague with oral ciprofloxacin |
topic | Research Letter |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382724/ https://www.ncbi.nlm.nih.gov/pubmed/28125398 http://dx.doi.org/10.3201/eid2303.161212 |
work_keys_str_mv | AT apangutitus successfultreatmentofhumanplaguewithoralciprofloxacin AT griffithkevin successfultreatmentofhumanplaguewithoralciprofloxacin AT abarujanet successfultreatmentofhumanplaguewithoralciprofloxacin AT candinigordian successfultreatmentofhumanplaguewithoralciprofloxacin AT apioharriet successfultreatmentofhumanplaguewithoralciprofloxacin AT okothfelix successfultreatmentofhumanplaguewithoralciprofloxacin AT okellorobert successfultreatmentofhumanplaguewithoralciprofloxacin AT kaggwajohn successfultreatmentofhumanplaguewithoralciprofloxacin AT acayosarah successfultreatmentofhumanplaguewithoralciprofloxacin AT ezamageoffrey successfultreatmentofhumanplaguewithoralciprofloxacin AT yockeybrook successfultreatmentofhumanplaguewithoralciprofloxacin AT sextonchristopher successfultreatmentofhumanplaguewithoralciprofloxacin AT schriefermartin successfultreatmentofhumanplaguewithoralciprofloxacin AT mbiddeedwardkatongole successfultreatmentofhumanplaguewithoralciprofloxacin AT meadpaul successfultreatmentofhumanplaguewithoralciprofloxacin |