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Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014

Despite control efforts, Mycobacterium bovis incidence among cattle remains high in parts of England, Wales, and Northern Ireland, attracting political and public health interest in potential spread from animals to humans. To determine incidence among humans and to identify associated factors, we co...

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Autores principales: Davidson, Jennifer A., Loutet, Miranda G., O’Connor, Catherine, Kearns, Cathriona, Smith, Robert M.M., Lalor, Maeve K., Thomas, H. Lucy, Abubakar, Ibrahim, Zenner, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382737/
https://www.ncbi.nlm.nih.gov/pubmed/28220748
http://dx.doi.org/10.3201/eid2303.161408
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author Davidson, Jennifer A.
Loutet, Miranda G.
O’Connor, Catherine
Kearns, Cathriona
Smith, Robert M.M.
Lalor, Maeve K.
Thomas, H. Lucy
Abubakar, Ibrahim
Zenner, Dominik
author_facet Davidson, Jennifer A.
Loutet, Miranda G.
O’Connor, Catherine
Kearns, Cathriona
Smith, Robert M.M.
Lalor, Maeve K.
Thomas, H. Lucy
Abubakar, Ibrahim
Zenner, Dominik
author_sort Davidson, Jennifer A.
collection PubMed
description Despite control efforts, Mycobacterium bovis incidence among cattle remains high in parts of England, Wales, and Northern Ireland, attracting political and public health interest in potential spread from animals to humans. To determine incidence among humans and to identify associated factors, we conducted a retrospective cohort analysis of human M. bovis cases in England, Wales, and Northern Ireland during 2002–2014. We identified 357 cases and observed increased annual case numbers (from 17 to 35) and rates. Most patients were >65 years of age and born in the United Kingdom. The median age of UK-born patients decreased over time. For 74% of patients, exposure to risk factors accounting for M. bovis acquisition, most frequently consumption of unpasteurized milk, was known. Despite the small increase in case numbers and reduction in patient age, M. bovis infection of humans in England, Wales, and Northern Ireland remains rare.
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spelling pubmed-53827372017-04-06 Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014 Davidson, Jennifer A. Loutet, Miranda G. O’Connor, Catherine Kearns, Cathriona Smith, Robert M.M. Lalor, Maeve K. Thomas, H. Lucy Abubakar, Ibrahim Zenner, Dominik Emerg Infect Dis Synopsis Despite control efforts, Mycobacterium bovis incidence among cattle remains high in parts of England, Wales, and Northern Ireland, attracting political and public health interest in potential spread from animals to humans. To determine incidence among humans and to identify associated factors, we conducted a retrospective cohort analysis of human M. bovis cases in England, Wales, and Northern Ireland during 2002–2014. We identified 357 cases and observed increased annual case numbers (from 17 to 35) and rates. Most patients were >65 years of age and born in the United Kingdom. The median age of UK-born patients decreased over time. For 74% of patients, exposure to risk factors accounting for M. bovis acquisition, most frequently consumption of unpasteurized milk, was known. Despite the small increase in case numbers and reduction in patient age, M. bovis infection of humans in England, Wales, and Northern Ireland remains rare. Centers for Disease Control and Prevention 2017-03 /pmc/articles/PMC5382737/ /pubmed/28220748 http://dx.doi.org/10.3201/eid2303.161408 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Davidson, Jennifer A.
Loutet, Miranda G.
O’Connor, Catherine
Kearns, Cathriona
Smith, Robert M.M.
Lalor, Maeve K.
Thomas, H. Lucy
Abubakar, Ibrahim
Zenner, Dominik
Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014
title Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014
title_full Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014
title_fullStr Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014
title_full_unstemmed Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014
title_short Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014
title_sort epidemiology of mycobacterium bovis disease in humans in england, wales, and northern ireland, 2002–2014
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382737/
https://www.ncbi.nlm.nih.gov/pubmed/28220748
http://dx.doi.org/10.3201/eid2303.161408
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