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pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia

Although pyrazinamide is commonly used for tuberculosis treatment, drug-susceptibility testing is not routinely available. We found polymorphisms in the pncA gene for 70% of multidrug-resistant and 96% of extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa and Georgia. A...

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Detalles Bibliográficos
Autores principales:	Allana, Salim, Shashkina, Elena, Mathema, Barun, Bablishvili, Nino, Tukvadze, Nestani, Shah, N. Sarita, Kempker, Russell R., Blumberg, Henry M., Moodley, Pravi, Mlisana, Koleka, Brust, James C.M., Gandhi, Neel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Centers for Disease Control and Prevention 2017
Materias:	Dispatch
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382742/ https://www.ncbi.nlm.nih.gov/pubmed/28221108 http://dx.doi.org/10.3201/eid2303.161034

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