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Operationalizing compensation over time in neurodegenerative disease
In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long et al. present two mathematical models of compensation over time and their operationalisation for neuroimaging.
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382953/ https://www.ncbi.nlm.nih.gov/pubmed/28334888 http://dx.doi.org/10.1093/brain/awx022 |
| _version_ | 1782520197713756160 |
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| author | Gregory, Sarah Long, Jeffrey D. Klöppel, Stefan Razi, Adeel Scheller, Elisa Minkova, Lora Papoutsi, Marina Mills, James A. Durr, Alexandra Leavitt, Blair R. Roos, Raymund A. C. Stout, Julie C. Scahill, Rachael I. Langbehn, Douglas R. Tabrizi, Sarah J. Rees, Geraint |
| author_facet | Gregory, Sarah Long, Jeffrey D. Klöppel, Stefan Razi, Adeel Scheller, Elisa Minkova, Lora Papoutsi, Marina Mills, James A. Durr, Alexandra Leavitt, Blair R. Roos, Raymund A. C. Stout, Julie C. Scahill, Rachael I. Langbehn, Douglas R. Tabrizi, Sarah J. Rees, Geraint |
| author_sort | Gregory, Sarah |
| collection | PubMed |
| description | In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long et al. present two mathematical models of compensation over time and their operationalisation for neuroimaging. |
| format | Online Article Text |
| id | pubmed-5382953 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-53829532017-04-11 Operationalizing compensation over time in neurodegenerative disease Gregory, Sarah Long, Jeffrey D. Klöppel, Stefan Razi, Adeel Scheller, Elisa Minkova, Lora Papoutsi, Marina Mills, James A. Durr, Alexandra Leavitt, Blair R. Roos, Raymund A. C. Stout, Julie C. Scahill, Rachael I. Langbehn, Douglas R. Tabrizi, Sarah J. Rees, Geraint Brain Dorsal column In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long et al. present two mathematical models of compensation over time and their operationalisation for neuroimaging. Oxford University Press 2017-04 2017-02-23 /pmc/articles/PMC5382953/ /pubmed/28334888 http://dx.doi.org/10.1093/brain/awx022 Text en © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Dorsal column Gregory, Sarah Long, Jeffrey D. Klöppel, Stefan Razi, Adeel Scheller, Elisa Minkova, Lora Papoutsi, Marina Mills, James A. Durr, Alexandra Leavitt, Blair R. Roos, Raymund A. C. Stout, Julie C. Scahill, Rachael I. Langbehn, Douglas R. Tabrizi, Sarah J. Rees, Geraint Operationalizing compensation over time in neurodegenerative disease |
| title | Operationalizing compensation over time in neurodegenerative disease |
| title_full | Operationalizing compensation over time in neurodegenerative disease |
| title_fullStr | Operationalizing compensation over time in neurodegenerative disease |
| title_full_unstemmed | Operationalizing compensation over time in neurodegenerative disease |
| title_short | Operationalizing compensation over time in neurodegenerative disease |
| title_sort | operationalizing compensation over time in neurodegenerative disease |
| topic | Dorsal column |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382953/ https://www.ncbi.nlm.nih.gov/pubmed/28334888 http://dx.doi.org/10.1093/brain/awx022 |
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