Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model

The envelope glycoproteins (Envs) of HIV-1 continuously evolve in the host by random mutations and recombination events. The resulting diversity of Env variants circulating in the population and their continuing diversification process limit the efficacy of AIDS vaccines. We examined the historic ch...

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Detalles Bibliográficos
Autores principales: DeLeon, Orlando, Hodis, Hagit, O’Malley, Yunxia, Johnson, Jacklyn, Salimi, Hamid, Zhai, Yinjie, Winter, Elizabeth, Remec, Claire, Eichelberger, Noah, Van Cleave, Brandon, Puliadi, Ramya, Harrington, Robert D., Stapleton, Jack T., Haim, Hillel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383018/
https://www.ncbi.nlm.nih.gov/pubmed/28384158
http://dx.doi.org/10.1371/journal.pbio.2001549

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