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Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients

BACKGROUND AND PURPOSE: Osteoid osteoma is a benign skeletal tumour that accounts for 2–3% of all bone tumours. The male-to-female ratio is around 4:1 and it predominates in children and young adults. The most common symptom is pain, frequently at night-time. Historically the main form of treatment...

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Autores principales: Nijland, H., Gerbers, J. G., Bulstra, S. K., Overbosch, J., Stevens, M., Jutte, P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383031/
https://www.ncbi.nlm.nih.gov/pubmed/28384223
http://dx.doi.org/10.1371/journal.pone.0169171
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author Nijland, H.
Gerbers, J. G.
Bulstra, S. K.
Overbosch, J.
Stevens, M.
Jutte, P. C.
author_facet Nijland, H.
Gerbers, J. G.
Bulstra, S. K.
Overbosch, J.
Stevens, M.
Jutte, P. C.
author_sort Nijland, H.
collection PubMed
description BACKGROUND AND PURPOSE: Osteoid osteoma is a benign skeletal tumour that accounts for 2–3% of all bone tumours. The male-to-female ratio is around 4:1 and it predominates in children and young adults. The most common symptom is pain, frequently at night-time. Historically the main form of treatment has been surgical excision. With the development of Radiofrequency Ablation (RFA) there is a percutaneus alternative. Success rates of RFA are lower but the main advantage is the minimal invasive character of the therapy and the low complication rate. As a result of the minimal invasiveness the hospitalization- and rehabilitation periods are relatively short. However, in current literature no values for accuracy and precision are known for the CT-guided positioning. METHODS: Accuracy and precision of the needle position are determined for 86 procedures. Furthermore the population is divided into groups based on tumour diameter, location and procedure outcome. RESULTS: The clinical success rate was 81.4%. In 79% of procedures complete ablation was achieved. Accuracy was 2.84 mm on average, precision was 2.94 mm. Accuracy was significantly lower in more profound lesions. Accuracy in tibia and fibula was significantly higher compared to the femur. No significant difference was found between different tumour diameters. INTERPRETATION: The accuracy and precision found are considered good. Needle position is of major importance for procedure outcomes. The question however rises how the results of this therapy will turn out in treatment of larger tumours.
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spelling pubmed-53830312017-05-03 Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients Nijland, H. Gerbers, J. G. Bulstra, S. K. Overbosch, J. Stevens, M. Jutte, P. C. PLoS One Research Article BACKGROUND AND PURPOSE: Osteoid osteoma is a benign skeletal tumour that accounts for 2–3% of all bone tumours. The male-to-female ratio is around 4:1 and it predominates in children and young adults. The most common symptom is pain, frequently at night-time. Historically the main form of treatment has been surgical excision. With the development of Radiofrequency Ablation (RFA) there is a percutaneus alternative. Success rates of RFA are lower but the main advantage is the minimal invasive character of the therapy and the low complication rate. As a result of the minimal invasiveness the hospitalization- and rehabilitation periods are relatively short. However, in current literature no values for accuracy and precision are known for the CT-guided positioning. METHODS: Accuracy and precision of the needle position are determined for 86 procedures. Furthermore the population is divided into groups based on tumour diameter, location and procedure outcome. RESULTS: The clinical success rate was 81.4%. In 79% of procedures complete ablation was achieved. Accuracy was 2.84 mm on average, precision was 2.94 mm. Accuracy was significantly lower in more profound lesions. Accuracy in tibia and fibula was significantly higher compared to the femur. No significant difference was found between different tumour diameters. INTERPRETATION: The accuracy and precision found are considered good. Needle position is of major importance for procedure outcomes. The question however rises how the results of this therapy will turn out in treatment of larger tumours. Public Library of Science 2017-04-06 /pmc/articles/PMC5383031/ /pubmed/28384223 http://dx.doi.org/10.1371/journal.pone.0169171 Text en © 2017 Nijland et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Nijland, H.
Gerbers, J. G.
Bulstra, S. K.
Overbosch, J.
Stevens, M.
Jutte, P. C.
Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients
title Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients
title_full Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients
title_fullStr Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients
title_full_unstemmed Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients
title_short Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients
title_sort evaluation of accuracy and precision of ct-guidance in radiofrequency ablation for osteoid osteoma in 86 patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383031/
https://www.ncbi.nlm.nih.gov/pubmed/28384223
http://dx.doi.org/10.1371/journal.pone.0169171
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