Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test – Demonstrated in vitro and ex vivo

INTRODUCTION: Canine models of severe haemophilia resemble their human equivalents both regarding clinical bleeding phenotype and response to treatment. Therefore pre-clinical studies in haemophilia dogs have allowed researchers to make valuable translational predictions regarding the potency and ef...

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Detalles Bibliográficos
Autores principales: Madsen, Daniel Elenius, Nichols, Timothy C., Merricks, Elizabeth P., Waters, Emily K., Wiinberg, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383133/
https://www.ncbi.nlm.nih.gov/pubmed/28384182
http://dx.doi.org/10.1371/journal.pone.0175030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383133/
https://www.ncbi.nlm.nih.gov/pubmed/28384182
http://dx.doi.org/10.1371/journal.pone.0175030

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