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Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance

To evaluate the effects of single-dose enrofloxacin (ERFX) on fever and blood properties in 68 Thoroughbred racehorses after long-distance transportation, horses were assigned to receive ERFX (5 mg/kg, IV; ERFX group; n=52) or saline (0.9% NaCl) solution (50 ml, IV; control group; n=16) ≤1 hr before...

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Autores principales: ENDO, Yoshiro, ISHIKAWA, Yuhiro, ARIMA, Daisuke, MAE, Naomi, IWAMOTO, Yohei, KOROSUE, Kenji, TSUZUKI, Nao, HOBO, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383162/
https://www.ncbi.nlm.nih.gov/pubmed/28111418
http://dx.doi.org/10.1292/jvms.16-0465
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author ENDO, Yoshiro
ISHIKAWA, Yuhiro
ARIMA, Daisuke
MAE, Naomi
IWAMOTO, Yohei
KOROSUE, Kenji
TSUZUKI, Nao
HOBO, Seiji
author_facet ENDO, Yoshiro
ISHIKAWA, Yuhiro
ARIMA, Daisuke
MAE, Naomi
IWAMOTO, Yohei
KOROSUE, Kenji
TSUZUKI, Nao
HOBO, Seiji
author_sort ENDO, Yoshiro
collection PubMed
description To evaluate the effects of single-dose enrofloxacin (ERFX) on fever and blood properties in 68 Thoroughbred racehorses after long-distance transportation, horses were assigned to receive ERFX (5 mg/kg, IV; ERFX group; n=52) or saline (0.9% NaCl) solution (50 ml, IV; control group; n=16) ≤1 hr before transportation. Horses were transported 1,122 km using commercial vans over the course of approximately 21 hr. Clinical examinations and hematologic analyses were performed before and after transportation. Rectal temperatures, white blood cell counts and serum amyloid A concentration of ERFX group were significantly lower than control group (P<0.01, P<0.01 and P<0.05, respectively). In conclusion, these results show ERFX administration just before transportation is effective at preventing transportation-associated fever in adult Thoroughbred racehorses.
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spelling pubmed-53831622017-04-11 Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance ENDO, Yoshiro ISHIKAWA, Yuhiro ARIMA, Daisuke MAE, Naomi IWAMOTO, Yohei KOROSUE, Kenji TSUZUKI, Nao HOBO, Seiji J Vet Med Sci Internal Medicine To evaluate the effects of single-dose enrofloxacin (ERFX) on fever and blood properties in 68 Thoroughbred racehorses after long-distance transportation, horses were assigned to receive ERFX (5 mg/kg, IV; ERFX group; n=52) or saline (0.9% NaCl) solution (50 ml, IV; control group; n=16) ≤1 hr before transportation. Horses were transported 1,122 km using commercial vans over the course of approximately 21 hr. Clinical examinations and hematologic analyses were performed before and after transportation. Rectal temperatures, white blood cell counts and serum amyloid A concentration of ERFX group were significantly lower than control group (P<0.01, P<0.01 and P<0.05, respectively). In conclusion, these results show ERFX administration just before transportation is effective at preventing transportation-associated fever in adult Thoroughbred racehorses. The Japanese Society of Veterinary Science 2017-01-22 2017-03 /pmc/articles/PMC5383162/ /pubmed/28111418 http://dx.doi.org/10.1292/jvms.16-0465 Text en ©2017 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
ENDO, Yoshiro
ISHIKAWA, Yuhiro
ARIMA, Daisuke
MAE, Naomi
IWAMOTO, Yohei
KOROSUE, Kenji
TSUZUKI, Nao
HOBO, Seiji
Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance
title Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance
title_full Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance
title_fullStr Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance
title_full_unstemmed Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance
title_short Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance
title_sort effects of pre-shipping enrofloxacin administration on fever and blood properties in adult thoroughbred racehorses transported a long distance
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383162/
https://www.ncbi.nlm.nih.gov/pubmed/28111418
http://dx.doi.org/10.1292/jvms.16-0465
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