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In-depth study of DNA binding of Cys(2)His(2) finger domains in testis zinc-finger protein

Previously, we identified that both fingers 1 and 2 in the three Cys(2)His(2) zinc-finger domains (TZD) of testis zinc-finger protein specifically bind to its cognate DNA; however, finger 3 is non-sequence–specific. To gain insights into the interaction mechanism, here we further investigated the DN...

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Detalles Bibliográficos
Autores principales: Chou, Chun-Chi, Wei, Shu-Yi, Lou, Yuan-Chao, Chen, Chinpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383199/
https://www.ncbi.nlm.nih.gov/pubmed/28384299
http://dx.doi.org/10.1371/journal.pone.0175051