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Production of putative enhanced oral cholera vaccine strains that express toxin-coregulated pilus

The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V. cholerae to be non-toxigenic and to express the protective protein colonization factor, toxin-coregulated pi...

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Detalles Bibliográficos
Autores principales: Hauke, Caitlyn A., Taylor, Ronald K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383245/
https://www.ncbi.nlm.nih.gov/pubmed/28384206
http://dx.doi.org/10.1371/journal.pone.0175170