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Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction

Growth deficits are common in cystic fibrosis (CF), but their cause is complex, with contributions from exocrine pancreatic insufficiency, pulmonary complications, gastrointestinal obstructions, and endocrine abnormalities. The CF mouse model displays similar growth impairment despite exocrine pancr...

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Detalles Bibliográficos
Autores principales: Darrah, Rebecca, Bederman, Ilya, Vitko, Megan, Valerio, Dana M., Drumm, Mitchell L., Hodges, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383306/
https://www.ncbi.nlm.nih.gov/pubmed/28384265
http://dx.doi.org/10.1371/journal.pone.0175467