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Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice

Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into epoxyeicosatrienoic acids (EETs), which play an important role in blood pressure regulation, protection against ischemia-reperfusion injury, angiogenesis, and inflammation. Epoxide hydrolases metabolize EETs to their corresponding d...

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Detalles Bibliográficos
Autores principales:	Hoopes, Samantha L., Gruzdev, Artiom, Edin, Matthew L., Graves, Joan P., Bradbury, J. Alyce, Flake, Gordon P., Lih, Fred B., DeGraff, Laura M., Zeldin, Darryl C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383309/ https://www.ncbi.nlm.nih.gov/pubmed/28384353 http://dx.doi.org/10.1371/journal.pone.0175348

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