Cargando…
Host cell-derived lactate functions as an effector molecule in Neisseria meningitidis microcolony dispersal
The development of meningococcal disease, caused by the human pathogen Neisseria meningitidis, is preceded by the colonization of the epithelial layer in the nasopharynx. After initial adhesion to host cells meningococci form aggregates, through pilus-pilus interactions, termed microcolonies from wh...
Autores principales: | Sigurlásdóttir, Sara, Engman, Jakob, Eriksson, Olaspers Sara, Saroj, Sunil D., Zguna, Nadezda, Lloris-Garcerá, Pilar, Ilag, Leopold L., Jonsson, Ann-Beth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383330/ https://www.ncbi.nlm.nih.gov/pubmed/28384279 http://dx.doi.org/10.1371/journal.ppat.1006251 |
Ejemplares similares
-
Lactate-Induced Dispersal of Neisseria meningitidis Microcolonies Is Mediated by Changes in Cell Density and Pilus Retraction and Is Influenced by Temperature Change
por: Sigurlásdóttir, Sara, et al.
Publicado: (2021) -
Deletion of D-Lactate Dehydrogenase A in Neisseria meningitidis Promotes Biofilm Formation Through Increased Autolysis and Extracellular DNA Release
por: Sigurlásdóttir, Sara, et al.
Publicado: (2019) -
Characterization of motility and piliation in pathogenic Neisseria
por: Eriksson, Jens, et al.
Publicado: (2015) -
Commensal Neisseria cinerea impairs Neisseria meningitidis microcolony development and reduces pathogen colonisation of epithelial cells
por: Custodio, Rafael, et al.
Publicado: (2020) -
DNA Blocks the Lethal Effect of Human Beta-Defensin 2 Against Neisseria meningitidis
por: Wassing, Gabriela M., et al.
Publicado: (2021)