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Domestic chickens activate a piRNA defense against avian leukosis virus

PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens. Here we reported that all active TEs in the chicken germ line are targeted by piRNAs, and as TEs lose their a...

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Detalles Bibliográficos
Autores principales: Sun, Yu Huining, Xie, Li Huitong, Zhuo, Xiaoyu, Chen, Qiang, Ghoneim, Dalia, Zhang, Bin, Jagne, Jarra, Yang, Chengbo, Li, Xin Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383398/
https://www.ncbi.nlm.nih.gov/pubmed/28384097
http://dx.doi.org/10.7554/eLife.24695