Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration

Bone marrow stem and progenitor cells can differentiate into a range of non-hematopoietic cell types, including retinal pigment epithelium (RPE)-like cells. In this study, we programmed bone marrow-derived cells (BMDCs) ex vivo by inserting a stable RPE65 transgene using a lentiviral vector. We test...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoping, Pay, S. Louise, Yan, Yuanqing, Thomas, James, Lewin, Alfred S., Chang, Lung-Ji, Grant, Maria B., Boulton, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383551/
https://www.ncbi.nlm.nih.gov/pubmed/28202390
http://dx.doi.org/10.1016/j.ymthe.2017.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383551/
https://www.ncbi.nlm.nih.gov/pubmed/28202390
http://dx.doi.org/10.1016/j.ymthe.2017.01.015

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