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Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics

Innovations in next-generation sequencing technology have introduced new avenues in microbial studies through “omics” approaches. This technology has considerably augmented the knowledge of the microbial world without isolation prior to their identification. With an enormous volume of bacterial “omi...

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Autores principales: Parmar, Krupa M., Gaikwad, Saurabh L., Dhakephalkar, Prashant K., Kothari, Ramesh, Singh, Ravindra Pal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383658/
https://www.ncbi.nlm.nih.gov/pubmed/28439260
http://dx.doi.org/10.3389/fmicb.2017.00559
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author Parmar, Krupa M.
Gaikwad, Saurabh L.
Dhakephalkar, Prashant K.
Kothari, Ramesh
Singh, Ravindra Pal
author_facet Parmar, Krupa M.
Gaikwad, Saurabh L.
Dhakephalkar, Prashant K.
Kothari, Ramesh
Singh, Ravindra Pal
author_sort Parmar, Krupa M.
collection PubMed
description Innovations in next-generation sequencing technology have introduced new avenues in microbial studies through “omics” approaches. This technology has considerably augmented the knowledge of the microbial world without isolation prior to their identification. With an enormous volume of bacterial “omics” data, considerable attempts have been recently invested to improve an insight into virosphere. The interplay between bacteriophages and their host has created a significant influence on the biogeochemical cycles, microbial diversity, and bacterial population regulation. This review highlights various concepts such as genomics, transcriptomics, proteomics, and metabolomics to infer the phylogenetic affiliation and function of bacteriophages and their impact on diverse microbial communities. Omics technologies illuminate the role of bacteriophage in an environment, the influences of phage proteins on the bacterial host and provide information about the genes important for interaction with bacteria. These investigations will reveal some of bio-molecules and biomarkers of the novel phage which demand to be unveiled.
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spelling pubmed-53836582017-04-24 Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics Parmar, Krupa M. Gaikwad, Saurabh L. Dhakephalkar, Prashant K. Kothari, Ramesh Singh, Ravindra Pal Front Microbiol Microbiology Innovations in next-generation sequencing technology have introduced new avenues in microbial studies through “omics” approaches. This technology has considerably augmented the knowledge of the microbial world without isolation prior to their identification. With an enormous volume of bacterial “omics” data, considerable attempts have been recently invested to improve an insight into virosphere. The interplay between bacteriophages and their host has created a significant influence on the biogeochemical cycles, microbial diversity, and bacterial population regulation. This review highlights various concepts such as genomics, transcriptomics, proteomics, and metabolomics to infer the phylogenetic affiliation and function of bacteriophages and their impact on diverse microbial communities. Omics technologies illuminate the role of bacteriophage in an environment, the influences of phage proteins on the bacterial host and provide information about the genes important for interaction with bacteria. These investigations will reveal some of bio-molecules and biomarkers of the novel phage which demand to be unveiled. Frontiers Media S.A. 2017-04-07 /pmc/articles/PMC5383658/ /pubmed/28439260 http://dx.doi.org/10.3389/fmicb.2017.00559 Text en Copyright © 2017 Parmar, Gaikwad, Dhakephalkar, Kothari and Singh. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Parmar, Krupa M.
Gaikwad, Saurabh L.
Dhakephalkar, Prashant K.
Kothari, Ramesh
Singh, Ravindra Pal
Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics
title Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics
title_full Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics
title_fullStr Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics
title_full_unstemmed Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics
title_short Intriguing Interaction of Bacteriophage-Host Association: An Understanding in the Era of Omics
title_sort intriguing interaction of bacteriophage-host association: an understanding in the era of omics
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383658/
https://www.ncbi.nlm.nih.gov/pubmed/28439260
http://dx.doi.org/10.3389/fmicb.2017.00559
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