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Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults

Growing evidence suggests a distinction between water intake necessary for maintaining a euhydrated state, and water intake considered to be adequate from a perspective of long-term health. Previously, we have proposed that maintaining a 24-h urine osmolality (U(Osm)) of ⩽500 mOsm/kg is a desirable...

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Autores principales: Perrier, E T, Bottin, J H, Vecchio, M, Lemetais, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383926/
https://www.ncbi.nlm.nih.gov/pubmed/28145416
http://dx.doi.org/10.1038/ejcn.2016.269
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author Perrier, E T
Bottin, J H
Vecchio, M
Lemetais, G
author_facet Perrier, E T
Bottin, J H
Vecchio, M
Lemetais, G
author_sort Perrier, E T
collection PubMed
description Growing evidence suggests a distinction between water intake necessary for maintaining a euhydrated state, and water intake considered to be adequate from a perspective of long-term health. Previously, we have proposed that maintaining a 24-h urine osmolality (U(Osm)) of ⩽500 mOsm/kg is a desirable target for urine concentration to ensure sufficient urinary output to reduce renal health risk and circulating vasopressin. In clinical practice and field monitoring, the measurement of U(Osm) is not practical. In this analysis, we calculate criterion values for urine-specific gravity (U(SG)) and urine color (U(Col)), two measures which have broad applicability in clinical and field settings. A receiver operating characteristic curve analysis performed on 817 urine samples demonstrates that a U(SG) ⩾1.013 detects U(Osm)>500 mOsm/kg with very high accuracy (AUC 0.984), whereas a subject-assessed U(Col)⩾4 offers high sensitivity and moderate specificity (AUC 0.831) for detecting U(Osm) >500 m Osm/kg.
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spelling pubmed-53839262017-04-23 Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults Perrier, E T Bottin, J H Vecchio, M Lemetais, G Eur J Clin Nutr Short Communication Growing evidence suggests a distinction between water intake necessary for maintaining a euhydrated state, and water intake considered to be adequate from a perspective of long-term health. Previously, we have proposed that maintaining a 24-h urine osmolality (U(Osm)) of ⩽500 mOsm/kg is a desirable target for urine concentration to ensure sufficient urinary output to reduce renal health risk and circulating vasopressin. In clinical practice and field monitoring, the measurement of U(Osm) is not practical. In this analysis, we calculate criterion values for urine-specific gravity (U(SG)) and urine color (U(Col)), two measures which have broad applicability in clinical and field settings. A receiver operating characteristic curve analysis performed on 817 urine samples demonstrates that a U(SG) ⩾1.013 detects U(Osm)>500 mOsm/kg with very high accuracy (AUC 0.984), whereas a subject-assessed U(Col)⩾4 offers high sensitivity and moderate specificity (AUC 0.831) for detecting U(Osm) >500 m Osm/kg. Nature Publishing Group 2017-04 2017-02-01 /pmc/articles/PMC5383926/ /pubmed/28145416 http://dx.doi.org/10.1038/ejcn.2016.269 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Short Communication
Perrier, E T
Bottin, J H
Vecchio, M
Lemetais, G
Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
title Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
title_full Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
title_fullStr Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
title_full_unstemmed Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
title_short Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
title_sort criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383926/
https://www.ncbi.nlm.nih.gov/pubmed/28145416
http://dx.doi.org/10.1038/ejcn.2016.269
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