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Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6

There is a need for an improved vaccine for tuberculosis. ESAT-6 is a cardinal vaccine antigen with unique properties and is included in several vaccine candidates in development. ESAT-6 is also the core antigen in the IFN-γ release assays (IGRA) used to diagnose latent infection, rendering IGRA tes...

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Detalles Bibliográficos
Autores principales:	Ruhwald, Morten, de Thurah, Lena, Kuchaka, Davis, Zaher, Mostafa Rafaat, Salman, Ahmed M., Abdel-Ghaffar, Abdel-Rahman, Shoukry, Faten Aly, Michelsen, Sascha Wilk, Soborg, Bolette, Blauenfeldt, Thomas, Mpagama, Stellah, Hoff, Søren T., Agger, Else Marie, Rosenkrands, Ida, Aagard, Claus, Kibiki, Gibson, El-Sheikh, Nabila, Andersen, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384086/ https://www.ncbi.nlm.nih.gov/pubmed/28387329 http://dx.doi.org/10.1038/srep45969

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