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Treating Cancer by Targeting Telomeres and Telomerase
Telomerase is expressed in more than 85% of cancer cells. Tumor cells with metastatic potential may have a high telomerase activity, allowing cells to escape from the inhibition of cell proliferation due to shortened telomeres. Human telomerase primarily consists of two main components: hTERT, a cat...
Autores principales: | Ivancich, Marko, Schrank, Zachary, Wojdyla, Luke, Leviskas, Brandon, Kuckovic, Adijan, Sanjali, Ankita, Puri, Neelu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384178/ https://www.ncbi.nlm.nih.gov/pubmed/28218725 http://dx.doi.org/10.3390/antiox6010015 |
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