Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress

Other than genetic regulation of salt sensitivity of blood pressure, many factors have been shown to regulate renal sodium handling which contributes to long-term blood pressure regulation and have been extensively reviewed. Here we present our progress on the Na/K-ATPase signaling mediated sodium r...

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Detalles Bibliográficos
Autores principales: Liu, Jiang, Yan, Yanling, Nie, Ying, Shapiro, Joseph I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384181/
https://www.ncbi.nlm.nih.gov/pubmed/28257114
http://dx.doi.org/10.3390/antiox6010018
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author Liu, Jiang
Yan, Yanling
Nie, Ying
Shapiro, Joseph I.
author_facet Liu, Jiang
Yan, Yanling
Nie, Ying
Shapiro, Joseph I.
author_sort Liu, Jiang
collection PubMed
description Other than genetic regulation of salt sensitivity of blood pressure, many factors have been shown to regulate renal sodium handling which contributes to long-term blood pressure regulation and have been extensively reviewed. Here we present our progress on the Na/K-ATPase signaling mediated sodium reabsorption in renal proximal tubules, from cardiotonic steroids-mediated to reactive oxygen species (ROS)-mediated Na/K-ATPase signaling that contributes to experimental salt sensitivity.
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spelling pubmed-53841812017-04-10 Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress Liu, Jiang Yan, Yanling Nie, Ying Shapiro, Joseph I. Antioxidants (Basel) Review Other than genetic regulation of salt sensitivity of blood pressure, many factors have been shown to regulate renal sodium handling which contributes to long-term blood pressure regulation and have been extensively reviewed. Here we present our progress on the Na/K-ATPase signaling mediated sodium reabsorption in renal proximal tubules, from cardiotonic steroids-mediated to reactive oxygen species (ROS)-mediated Na/K-ATPase signaling that contributes to experimental salt sensitivity. MDPI 2017-03-02 /pmc/articles/PMC5384181/ /pubmed/28257114 http://dx.doi.org/10.3390/antiox6010018 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Jiang
Yan, Yanling
Nie, Ying
Shapiro, Joseph I.
Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
title Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
title_full Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
title_fullStr Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
title_full_unstemmed Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
title_short Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
title_sort na/k-atpase signaling and salt sensitivity: the role of oxidative stress
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384181/
https://www.ncbi.nlm.nih.gov/pubmed/28257114
http://dx.doi.org/10.3390/antiox6010018
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AT nieying nakatpasesignalingandsaltsensitivitytheroleofoxidativestress
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