PLGA-based dual targeted nanoparticles enhance miRNA transfection efficiency in hepatic carcinoma

Hepatic carcinoma (HCC) is a lethal disease associated with high morbidity and poor prognosis. Recently years, gene therapies have offered novel modalities to improve the prognosis of HCC patients. MicroRNA-99a (miR-99a) is frequently down-regulated in HCC, where it acts as a tumor suppressor. There...

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Detalles Bibliográficos
Autores principales: Cai, Chenlei, Xie, Yuexia, Wu, liangliang, Chen, Xiaojing, Liu, Hongmei, Zhou, Yan, Zou, Hanbing, Liu, Dejun, Zhao, Yanan, Kong, Xianming, Liu, Peifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384185/
https://www.ncbi.nlm.nih.gov/pubmed/28387375
http://dx.doi.org/10.1038/srep46250

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