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Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

It is widely accepted that dynamic and reversible tumour cell plasticity is required for metastasis, however, in vivo steps and molecular mechanisms are poorly elucidated. We demonstrate here that monocytic (mMDSC) and granulocytic (gMDSC) subsets of myeloid-derived suppressor cells infiltrate in th...

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Detalles Bibliográficos
Autores principales: Ouzounova, Maria, Lee, Eunmi, Piranlioglu, Raziye, El Andaloussi, Abdeljabar, Kolhe, Ravindra, Demirci, Mehmet F., Marasco, Daniela, Asm, Iskander, Chadli, Ahmed, Hassan, Khaled A., Thangaraju, Muthusamy, Zhou, Gang, Arbab, Ali S., Cowell, John K., Korkaya, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384228/
https://www.ncbi.nlm.nih.gov/pubmed/28382931
http://dx.doi.org/10.1038/ncomms14979