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A CD3/CD28 microbead-based HIV-1 viral outgrowth assay

AIMS: Latently infected resting CD4 T cells represent a major barrier to HIV-1 eradication efforts. The standard assays used for measuring this reservoir induce activation of resting CD4 T cells with either phytohaemagglutinin (PHA) with irradiated feeder cells, or with anti-CD3 antibodies. We desig...

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Detalles Bibliográficos
Autores principales:	Kuzmichev, Yury V, Veenhuis, Rebecca T, Pohlmeyer, Christopher W, Garliss, Caroline C, Walker-Sperling, Victoria EK, Blankson, Joel N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mediscript Ltd 2017
Materias:	Original Reaserch
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384271/ https://www.ncbi.nlm.nih.gov/pubmed/28435692

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