Cargando…

Inflammatory Cyclooxygenase Activity and PGE(2) Signaling in Models of Alzheimer’s Disease

The inflammatory response is a fundamental driving force in the pathogenesis of Alzheimer’s disease (AD). In the setting of accumulating immunogenic Aß peptide assemblies, microglia, the innate immune cells of the brain, generate a non-resolving immune response and fail to adequately clear accumulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johansson, Jenny U., Woodling, Nathaniel S., Shi, Ju, Andreasson, Katrin I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384338/ https://www.ncbi.nlm.nih.gov/pubmed/28413375 http://dx.doi.org/10.2174/1573395511666150707181414

Ejemplares similares

Microarray analysis of the in vivo response of microglia to Aβ peptides in mice with conditional deletion of the prostaglandin EP2 receptor
por: Johansson, Jenny U., et al.
Publicado: (2015)

The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
por: Esh, Christopher J., et al.
Publicado: (2021)

Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas
por: Akbari, Nasrin, et al.
Publicado: (2020)

Cyclooxygenase production of PGE(2) promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish
por: Thrikawala, Savini, et al.
Publicado: (2022)

The anti-inflammatory effect of cyclooxygenase inhibitors in fibroblast-like synoviocytes from the human temporomandibular joint results from the suppression of PGE2 production
por: Kawashima, Mutsumi, et al.
Publicado: (2013)

Shifting equilibriums in Alzheimer’s disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis
por: Gray, Sophie C., et al.
Publicado: (2020)

Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia
por: Abo-El Fetoh, Mohammed E., et al.
Publicado: (2022)

Cyclooxygenase 2 Promotes Proliferation and Invasion in Ovarian Cancer Cells via the PGE2/NF-κB Pathway
por: Zhang, Xiao, et al.
Publicado: (2019)

Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE(2) and 5-Hydroxy-PGD(2)
por: Nakashima, Fumie, et al.
Publicado: (2021)

Simultaneous Inhibition of PGE(2) and PGI(2) Signals Is Necessary to Suppress Hyperalgesia in Rat Inflammatory Pain Models
por: Sugita, Ryusuke, et al.
Publicado: (2016)

Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2
por: Jung, Hyo Young, et al.
Publicado: (2021)

Mitochondria Dysfunction in Frontotemporal Dementia/Amyotrophic Lateral Sclerosis: Lessons From Drosophila Models
por: Anoar, Sharifah, et al.
Publicado: (2021)

miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor
por: Li, Huanan, et al.
Publicado: (2016)

Electrophysiologic and anti‐inflammatorial effects of cyclooxygenase inhibition in epileptiform activity
por: Akunal Türel, Canan, et al.
Publicado: (2023)

Variability in the Analgesic Response to Ibuprofen Is Associated With Cyclooxygenase Activation in Inflammatory Pain
por: Theken, Katherine N., et al.
Publicado: (2019)

Anti-inflammatory Activity and PGE(2) Inhibitory Properties of Novel Phenylcarbamoylmethyl Ester-Containing Compounds
por: Barsoum, Flora, et al.
Publicado: (2009)

TLR Signalling Pathways Diverge in Their Ability to Induce PGE(2)
por: Salvi, Valentina, et al.
Publicado: (2016)

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer’s disease related pathology
por: Joshi, Amit U., et al.
Publicado: (2019)

Vanadium Compounds as Pro-Inflammatory Agents: Effects on Cyclooxygenases
por: Korbecki, Jan, et al.
Publicado: (2015)

The cyclooxygenases
por: Chandrasekharan, NV, et al.
Publicado: (2004)

DUSP-1 Induced by PGE(2) and PGE(1) Attenuates IL-1β-Activated MAPK Signaling, Leading to Suppression of NGF Expression in Human Intervertebral Disc Cells
por: Kusakabe, Takuya, et al.
Publicado: (2021)

Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling
por: Woodling, Nathaniel S., et al.
Publicado: (2020)

Active Smoking Increases Microsomal PGE(2)-Synthase-1/PGE-Receptor-4 Axis in Human Abdominal Aortic Aneurysms
por: Dilmé, Jaime-Félix, et al.
Publicado: (2014)

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold
por: Grabrucker, Andreas M, et al.
Publicado: (2011)

The Signaling Pathway of PGE(2) and Its Regulatory Role in T Cell Differentiation
por: An, Yang, et al.
Publicado: (2021)

Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE(2) and Cytokines
por: Linke, Bona, et al.
Publicado: (2017)

Immunohistochemical Expressions of Main PGE(2) Biosynthesis-related Enzymes and PGE(2) Receptor in Rat Nephrogenesis
por: Yamamoto, Emi, et al.
Publicado: (2011)

Consistent Inhibition of Cyclooxygenase Drives Macrophages towards the Inflammatory Phenotype
por: Na, Yi Rang, et al.
Publicado: (2015)

Cyclooxygenase Isoform Exchange Blocks Brain-Mediated Inflammatory Symptoms
por: Björk Wilhelms, Daniel, et al.
Publicado: (2016)

Drug Discovery of New Anti-Inflammatory Compounds by Targeting Cyclooxygenases
por: Burayk, Shady, et al.
Publicado: (2022)

Anti-inflammatory effects of PGE(2) in the lung: role of the EP(4) receptor subtype
por: Birrell, Mark A, et al.
Publicado: (2015)

Changing prostaglandin E2 (PGE(2)) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE(2) receptor EP2 and EP4
por: Huang, Qingqing, et al.
Publicado: (2021)

Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity
por: Kutil, Zsofia, et al.
Publicado: (2014)

Ciliary neurotrophic factor (CNTF) plus soluble CNTF receptor α increases cyclooxygenase-2 expression, PGE(2 )release and interferon-γ-induced CD40 in murine microglia
por: Lin, Hsiao-Wen, et al.
Publicado: (2009)

Mapping PTGERs to the Ovulatory Follicle: Regional Responses to the Ovulatory PGE2 Signal
por: Kim, Soon Ok, et al.
Publicado: (2016)

Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway
por: Ulivi, Valentina, et al.
Publicado: (2011)

Cannabinoid system and cyclooxygenases inhibitors
por: Păunescu, H, et al.
Publicado: (2011)

Synthesis and Biological Evaluation of Gentiopicroside Derivatives as Novel Cyclooxygenase-2 Inhibitors with Anti-Inflammatory Activity
por: Ren, Guojin, et al.
Publicado: (2023)

In-vitro and computational analysis of Urolithin-A for anti-inflammatory activity on Cyclooxygenase 2 (COX-2)
por: Revankar, Archana G., et al.
Publicado: (2023)

PTGES/PGE(2) signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
por: Wang, Tong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s9t4q13dku1htq4gkrkl36pt3q