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Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Recent clinical studies indicate that adoptive T-cell therapy and especially chimeric antigen receptor (CAR) T-cell therapy is a very potent and potentially curative treatment for B-lineage hematologic malignancies. Currently, autologous peripheral blood T cells are used for adoptive T-cell therapy....

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Detalles Bibliográficos
Autores principales:	Van Caeneghem, Yasmine, De Munter, Stijn, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich, Vandekerckhove, Bart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384408/ https://www.ncbi.nlm.nih.gov/pubmed/28405508 http://dx.doi.org/10.1080/2162402X.2017.1283460

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