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Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer’s disease
Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is linked to oxidative stress, altered amyloid precursor protein (APP) proteolysis, tau hyperphosphorylation and the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles (NFT). A growing body of evidence suggests that...
Autores principales: | Sawmiller, Darrell, Li, Song, Mori, Takashi, Habib, Ahsan, Rongo, David, Delic, Vedad, Bradshaw, Patrick C., Shytle, R. Douglas, Sanberg, Cyndy, Bickford, Paula, Tan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384415/ https://www.ncbi.nlm.nih.gov/pubmed/28413833 http://dx.doi.org/10.1016/j.heliyon.2017.e00279 |
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