Cargando…
Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo
Because of the potent graft-versus-tumor (GVT) effect, allogeneic stem cell transplantation (alloSCT) can be a curative therapy for hematological malignancies. However, relapse remains the most frequent cause of treatment failure, illustrating the necessity for development of adjuvant post-transplan...
Autores principales: | Thordardottir, Soley, Schaap, Nicolaas, Louer, Elja, Kester, Michel G. D., Falkenburg, J. H. Frederik, Jansen, Joop, Radstake, Timothy R. D., Hobo, Willemijn, Dolstra, Harry |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384421/ https://www.ncbi.nlm.nih.gov/pubmed/28405517 http://dx.doi.org/10.1080/2162402X.2017.1285991 |
Ejemplares similares
-
Clinically applicable CD34(+)-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses
por: van Eck van der Sluijs, Jesper, et al.
Publicado: (2021) -
Intraperitoneal infusion of ex vivo-cultured allogeneic NK cells in recurrent ovarian carcinoma patients (a phase I study)
por: Hoogstad-van Evert, Janneke, et al.
Publicado: (2019) -
Human CD34(+)-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8(+) T cell and NK cell responses in vitro and in vivo
por: van Eck van der Sluijs, Jesper, et al.
Publicado: (2023) -
Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8(+) T cells for adoptive immunotherapy
por: Mousset, Charlotte M., et al.
Publicado: (2018) -
A trispecific killer engager molecule against CLEC12A effectively induces NK cell mediated killing of AML cells
por: Arvindam, Upasana Sunil, et al.
Publicado: (2020)