A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development

Tubulin alpha 8 (Tuba8) is the most divergent member of the highly conserved alpha tubulin family, and uniquely lacks two key post-translational modification sites. It is abundantly expressed in testis and muscle, with lower levels in the brain. We previously identified homozygous hypomorphic TUBA8...

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Detalles Bibliográficos
Autores principales: Diggle, Christine P., Martinez-Garay, Isabel, Molnar, Zoltan, Brinkworth, Martin H., White, Ed, Fowler, Ewan, Hughes, Ruth, Hayward, Bruce E., Carr, Ian M., Watson, Christopher M., Crinnion, Laura, Asipu, Aruna, Woodman, Ben, Coletta, P. Louise, Markham, Alexander F., Dear, T. Neil, Bonthron, David T., Peckham, Michelle, Morrison, Ewan E., Sheridan, Eamonn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384676/
https://www.ncbi.nlm.nih.gov/pubmed/28388629
http://dx.doi.org/10.1371/journal.pone.0174264

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