Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice

Renal tubular epithelial-to-mesenchymal transition (EMT) and renal tubular interstitial fibrosis are the main pathological changes of diabetic nephropathy (DN), which is a common cause of end-stage renal disease. Previous studies have suggested that berberine (BBR) has antifibrotic effects in the ki...

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Detalles Bibliográficos
Autores principales: Yang, Guannan, Zhao, Zongjiang, Zhang, Xinxue, Wu, Amin, Huang, Yawei, Miao, Yonghui, Yang, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384688/
https://www.ncbi.nlm.nih.gov/pubmed/28408805
http://dx.doi.org/10.2147/DDDT.S124971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384688/
https://www.ncbi.nlm.nih.gov/pubmed/28408805
http://dx.doi.org/10.2147/DDDT.S124971

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