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Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice
Renal tubular epithelial-to-mesenchymal transition (EMT) and renal tubular interstitial fibrosis are the main pathological changes of diabetic nephropathy (DN), which is a common cause of end-stage renal disease. Previous studies have suggested that berberine (BBR) has antifibrotic effects in the ki...
Autores principales: | Yang, Guannan, Zhao, Zongjiang, Zhang, Xinxue, Wu, Amin, Huang, Yawei, Miao, Yonghui, Yang, Meijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384688/ https://www.ncbi.nlm.nih.gov/pubmed/28408805 http://dx.doi.org/10.2147/DDDT.S124971 |
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