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Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency
NAD(+) has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organismal homeostasis. Among the enzymes involved in its recycling, nicotinamide mononucleotide (NMN) deamidase is one of the key players in the bacterial pyridine nu...
Autores principales: | Martínez-Moñino, Ana Belén, Zapata-Pérez, Rubén, García-Saura, Antonio Ginés, Gil-Ortiz, Fernando, Pérez-Gilabert, Manuela, Sánchez-Ferrer, Álvaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384747/ https://www.ncbi.nlm.nih.gov/pubmed/28388636 http://dx.doi.org/10.1371/journal.pone.0174759 |
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