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Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior
The extracellular matrix (ECM) is a major regulator of cell behavior. Recent studies have indicated the importance of the physical properties of the ECM, including its stiffness, for cell migration and differentiation. Using actomyosin-generated forces, cells pull the ECM and sense stiffness via cel...
Autores principales: | Omachi, Tomohiro, Ichikawa, Takafumi, Kimura, Yasuhisa, Ueda, Kazumitsu, Kioka, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384775/ https://www.ncbi.nlm.nih.gov/pubmed/28388663 http://dx.doi.org/10.1371/journal.pone.0175324 |
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