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A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides
Mucorales are a group of basal fungi that includes the casual agents of the human emerging disease mucormycosis. Recent studies revealed that these pathogens activate an RNAi-based pathway to rapidly generate drug-resistant epimutant strains when exposed to stressful compounds such as the antifungal...
Autores principales: | Calo, Silvia, Nicolás, Francisco E., Lee, Soo Chan, Vila, Ana, Cervantes, Maria, Torres-Martinez, Santiago, Ruiz-Vazquez, Rosa M., Cardenas, Maria E., Heitman, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384783/ https://www.ncbi.nlm.nih.gov/pubmed/28339467 http://dx.doi.org/10.1371/journal.pgen.1006686 |
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