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Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients
The biologic plausibility of an association between type 2 diabetes mellitus (T2D) and lung cancer has received increasing attention, but the results of investigations remain largely inconclusive. In the present study we investigated the influence of the anti-diabetic drug metformin on the cytotoxic...
Autores principales: | Xiao, Zhiguang, Gaertner, Silvia, Morresi-Hauf, Alicia, Genzel, Rebecca, Duell, Thomas, Ullrich, Axel, Knyazev, Pjotr G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384889/ https://www.ncbi.nlm.nih.gov/pubmed/28391030 http://dx.doi.org/10.1016/j.neo.2017.02.011 |
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