HER2 testing in gastric cancer: results of a German expert meeting

Valid HER2 testing is essential for optimal therapy of patients with HER2-positive gastric cancer and the correct use of first-line chemotherapy. While testing for HER2 status in breast cancer is routinely performed, this is not the case for HER2 testing in gastric cancer and it is usually only perf...

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Autores principales: Lordick, Florian, Al-Batran, Salah-Eddin, Dietel, Manfred, Gaiser, Timo, Hofheinz, Ralf-Dieter, Kirchner, Thomas, Kreipe, Hans H., Lorenzen, Sylvie, Möhler, Markus, Quaas, Alexander, Röcken, Christoph, Rüschoff, Josef, Tannapfel, Andrea, Thuss-Patience, Peter, Baretton, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Review – Clinical Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384945/
https://www.ncbi.nlm.nih.gov/pubmed/28285403
http://dx.doi.org/10.1007/s00432-017-2374-x
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author Lordick, Florian
Al-Batran, Salah-Eddin
Dietel, Manfred
Gaiser, Timo
Hofheinz, Ralf-Dieter
Kirchner, Thomas
Kreipe, Hans H.
Lorenzen, Sylvie
Möhler, Markus
Quaas, Alexander
Röcken, Christoph
Rüschoff, Josef
Tannapfel, Andrea
Thuss-Patience, Peter
Baretton, Gustavo
author_facet Lordick, Florian
Al-Batran, Salah-Eddin
Dietel, Manfred
Gaiser, Timo
Hofheinz, Ralf-Dieter
Kirchner, Thomas
Kreipe, Hans H.
Lorenzen, Sylvie
Möhler, Markus
Quaas, Alexander
Röcken, Christoph
Rüschoff, Josef
Tannapfel, Andrea
Thuss-Patience, Peter
Baretton, Gustavo
author_sort Lordick, Florian
collection PubMed
description Valid HER2 testing is essential for optimal therapy of patients with HER2-positive gastric cancer and the correct use of first-line chemotherapy. While testing for HER2 status in breast cancer is routinely performed, this is not the case for HER2 testing in gastric cancer and it is usually only performed on clinician request. An interdisciplinary German expert group (pathologists and clinicians) took the challenges of HER2 testing in gastric cancer as an opportunity to address essential aspects and questions for the practical use of HER2 testing in this indication. The recommendations made in this manuscript reflect the consensus of all participants and reflect their opinions and long-term experience in this field.
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spelling pubmed-53849452017-04-24 HER2 testing in gastric cancer: results of a German expert meeting Lordick, Florian Al-Batran, Salah-Eddin Dietel, Manfred Gaiser, Timo Hofheinz, Ralf-Dieter Kirchner, Thomas Kreipe, Hans H. Lorenzen, Sylvie Möhler, Markus Quaas, Alexander Röcken, Christoph Rüschoff, Josef Tannapfel, Andrea Thuss-Patience, Peter Baretton, Gustavo J Cancer Res Clin Oncol Review – Clinical Oncology Valid HER2 testing is essential for optimal therapy of patients with HER2-positive gastric cancer and the correct use of first-line chemotherapy. While testing for HER2 status in breast cancer is routinely performed, this is not the case for HER2 testing in gastric cancer and it is usually only performed on clinician request. An interdisciplinary German expert group (pathologists and clinicians) took the challenges of HER2 testing in gastric cancer as an opportunity to address essential aspects and questions for the practical use of HER2 testing in this indication. The recommendations made in this manuscript reflect the consensus of all participants and reflect their opinions and long-term experience in this field. Springer Berlin Heidelberg 2017-03-11 2017 /pmc/articles/PMC5384945/ /pubmed/28285403 http://dx.doi.org/10.1007/s00432-017-2374-x Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review – Clinical Oncology
Lordick, Florian
Al-Batran, Salah-Eddin
Dietel, Manfred
Gaiser, Timo
Hofheinz, Ralf-Dieter
Kirchner, Thomas
Kreipe, Hans H.
Lorenzen, Sylvie
Möhler, Markus
Quaas, Alexander
Röcken, Christoph
Rüschoff, Josef
Tannapfel, Andrea
Thuss-Patience, Peter
Baretton, Gustavo
HER2 testing in gastric cancer: results of a German expert meeting
title HER2 testing in gastric cancer: results of a German expert meeting
title_full HER2 testing in gastric cancer: results of a German expert meeting
title_fullStr HER2 testing in gastric cancer: results of a German expert meeting
title_full_unstemmed HER2 testing in gastric cancer: results of a German expert meeting
title_short HER2 testing in gastric cancer: results of a German expert meeting
title_sort her2 testing in gastric cancer: results of a german expert meeting
topic Review – Clinical Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384945/
https://www.ncbi.nlm.nih.gov/pubmed/28285403
http://dx.doi.org/10.1007/s00432-017-2374-x
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