Dynamics of surface of lipid membranes: theoretical considerations and the ESR experiment

The effect of the surface layer of model membranes on their physical properties was discussed in this paper. The research involved a physical ESR experiment with the use of spin probes and computer simulation based on the Monte Carlo technique. Liposomes formed during the process of sonication of lecithin were scanned in an ESR spectrometer. The membrane surface layer model, represented by the system of electric dipoles arranged in rectangular or hexagonal matrices, was studied. The final states of computer simulations were presented as textures. It was found that in the gel phase some ordered domain structures are formed, while in the liquid–crystal phase we got complex textures comprising a plurality of gaps. The process of forming domain structures during the changing of the temperature and the phase transitions taking place in a dipole system as a function of dipole mobility (k-parameter) was presented. The results obtained imply that the head groups (represented by electric dipoles in the computer model) of the surface layer play a key role in membranes, affecting the properties of the entire membrane, which is particularly essential for transport processes. It also modified the characteristics of the membrane gel-liquid crystalline transition phase.