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Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma

BACKGROUND: Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a significant minority of patients. The Cambridge Chronic Subdural Haematoma Trial (CCSHT) was a randomised controlled study that showed placement of su...

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Autores principales: Guilfoyle, Mathew R., Hutchinson, Peter J. A., Santarius, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385189/
https://www.ncbi.nlm.nih.gov/pubmed/28349381
http://dx.doi.org/10.1007/s00701-017-3095-2
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author Guilfoyle, Mathew R.
Hutchinson, Peter J. A.
Santarius, Thomas
author_facet Guilfoyle, Mathew R.
Hutchinson, Peter J. A.
Santarius, Thomas
author_sort Guilfoyle, Mathew R.
collection PubMed
description BACKGROUND: Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a significant minority of patients. The Cambridge Chronic Subdural Haematoma Trial (CCSHT) was a randomised controlled study that showed placement of subdural drains for 48 h following burrhole evacuation significantly reduces the incidence of reoperation and improves survival at 6 months. The present study examined the long-term survival of the patients in the trial. METHODS: In the original trial patients at a single neurosurgical centre from 2004–2007 were randomly assigned to receive a drain (n = 108) or no drain (n = 107) following burrhole drainage of CSDH. We ascertained whether the trial patients were alive in February 2016—a minimum of 8 years following enrollment—via the UK NHS tracing service. Survival was compared between the trial groups and against expected survival for the UK general population matched for age and sex. RESULTS: At 5 years following surgery the drain group continued to have significantly better survival than the no drain patients (p = 0.027), but this was no longer apparent at 10 years. Survival of patients in the drain group did not differ significantly from that of the general population whereas patients who did not receive a drain had significantly lower survival than expected (p = 0.0006). CONCLUSION: Subdural drains following CSDH evacuation are associated with improved long-term survival, which appears similar to that expected for the general population of the same age and sex. All patients having burrhole CSDH evacuation should receive a drain as standard practice unless specifically contraindicated.
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spelling pubmed-53851892017-04-24 Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma Guilfoyle, Mathew R. Hutchinson, Peter J. A. Santarius, Thomas Acta Neurochir (Wien) Clinical Article - Neurosurgical Techniques BACKGROUND: Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a significant minority of patients. The Cambridge Chronic Subdural Haematoma Trial (CCSHT) was a randomised controlled study that showed placement of subdural drains for 48 h following burrhole evacuation significantly reduces the incidence of reoperation and improves survival at 6 months. The present study examined the long-term survival of the patients in the trial. METHODS: In the original trial patients at a single neurosurgical centre from 2004–2007 were randomly assigned to receive a drain (n = 108) or no drain (n = 107) following burrhole drainage of CSDH. We ascertained whether the trial patients were alive in February 2016—a minimum of 8 years following enrollment—via the UK NHS tracing service. Survival was compared between the trial groups and against expected survival for the UK general population matched for age and sex. RESULTS: At 5 years following surgery the drain group continued to have significantly better survival than the no drain patients (p = 0.027), but this was no longer apparent at 10 years. Survival of patients in the drain group did not differ significantly from that of the general population whereas patients who did not receive a drain had significantly lower survival than expected (p = 0.0006). CONCLUSION: Subdural drains following CSDH evacuation are associated with improved long-term survival, which appears similar to that expected for the general population of the same age and sex. All patients having burrhole CSDH evacuation should receive a drain as standard practice unless specifically contraindicated. Springer Vienna 2017-03-27 2017 /pmc/articles/PMC5385189/ /pubmed/28349381 http://dx.doi.org/10.1007/s00701-017-3095-2 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Clinical Article - Neurosurgical Techniques
Guilfoyle, Mathew R.
Hutchinson, Peter J. A.
Santarius, Thomas
Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
title Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
title_full Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
title_fullStr Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
title_full_unstemmed Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
title_short Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
title_sort improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
topic Clinical Article - Neurosurgical Techniques
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385189/
https://www.ncbi.nlm.nih.gov/pubmed/28349381
http://dx.doi.org/10.1007/s00701-017-3095-2
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